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Placenta-specific 8 limits IFNγ production by CD4 T cells in vitro and promotes establishment of inf...

Placenta-specific 8 limits IFNγ production by CD4 T cells in vitro and promotes establishment of inf...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2421429029

Placenta-specific 8 limits IFNγ production by CD4 T cells in vitro and promotes establishment of influenza-specific CD8 T cells in vivo

About this item

Full title

Placenta-specific 8 limits IFNγ production by CD4 T cells in vitro and promotes establishment of influenza-specific CD8 T cells in vivo

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-07, Vol.15 (7), p.e0235706

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

During type 1 immune responses, CD4 T helper 1 (Th1) cells and CD8 T cells are activated via IL-12 and contribute to the elimination of intracellular pathogens through interferon gamma (IFNγ) production. In this study, we identified Placenta-specific 8 (Plac8) as a gene that is uniquely expressed in Th1 CD4 T cells relative to other CD4 T cell subs...

Alternative Titles

Full title

Placenta-specific 8 limits IFNγ production by CD4 T cells in vitro and promotes establishment of influenza-specific CD8 T cells in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2421429029

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2421429029

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0235706

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