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Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer

Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2424465316

Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer

About this item

Full title

Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer

Publisher

San Francisco: Public Library of Science

Journal title

PLoS biology, 2020-06, Vol.18 (6), p.e3000732-e3000732

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Coordination of gene expression with nutrient availability supports proliferation and homeostasis and is shaped by protein acetylation. Yet how physiological/pathological signals link acetylation to specific gene expression programs and whether such responses are cell-type-specific is unclear. AMP-activated protein kinase (AMPK) is a key energy sen...

Alternative Titles

Full title

Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2424465316

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2424465316

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3000732

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