Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific...
Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Crimean-Congo hemorrhagic fever orthonairovirus (CCHFV) is one of the most widespread medically important arboviruses, causing human infections that result in mortality rates of up to 60%. We describe the selection of a high-affinity small protein (Affimer-NP) that binds specifically to the nucleoprotein (NP) of CCHFV. We demonstrate the interferen...
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Full title
Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests
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TN_cdi_plos_journals_2424467712
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2424467712
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ISSN
1935-2735,1935-2727
E-ISSN
1935-2735
DOI
10.1371/journal.pntd.0008364
