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Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokin...

Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2424468397

Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus

About this item

Full title

Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2020-06, Vol.16 (6), p.e1007998

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Post-traumatic osteoarthritis (PTOA) is associated with cartilage degradation, ultimately leading to disability and decrease of quality of life. Two key mechanisms have been suggested to occur in PTOA: tissue inflammation and abnormal biomechanical loading. Both mechanisms have been suggested to result in loss of cartilage proteoglycans, the source...

Alternative Titles

Full title

Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2424468397

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2424468397

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1007998

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