In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope...
In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction
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United States: Public Library of Science
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English
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United States: Public Library of Science
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[...]even for members of the HLA-A11 allele family that have very strict and limited C-anchor binding requirements, elution studies have demonstrated that only about 20% of the (self and viral) epitopes are exactly 9 amino acids in length [7]. [...]it seems critical that SARS-CoV-2 vaccine development take this aspect into account and test immunoge...
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In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction
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TN_cdi_plos_journals_2424469169
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2424469169
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008607