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In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope...

In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2424469169

In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction

About this item

Full title

In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2020-06, Vol.16 (6), p.e1008607-e1008607

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

[...]even for members of the HLA-A11 allele family that have very strict and limited C-anchor binding requirements, elution studies have demonstrated that only about 20% of the (self and viral) epitopes are exactly 9 amino acids in length [7]. [...]it seems critical that SARS-CoV-2 vaccine development take this aspect into account and test immunoge...

Alternative Titles

Full title

In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2424469169

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2424469169

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1008607

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