Anti-GD2 induced allodynia in rats can be reduced by pretreatment with DFMO
Anti-GD2 induced allodynia in rats can be reduced by pretreatment with DFMO
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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Background Anti-GD2 therapy with dinutuximab is effective in improving the survival of high-risk neuroblastoma patients in remission and after relapse. However, allodynia is the major dose-limiting side effect, hindering its use for neuroblastoma patients at higher doses and for other GD2-expressing malignancies. As polyamines can enhance neuronal...
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Full title
Anti-GD2 induced allodynia in rats can be reduced by pretreatment with DFMO
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TN_cdi_plos_journals_2426158852
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2426158852
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0236115
