The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of...
The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The membrane protein ANKH was known to prevent pathological mineralization of joints and was thought to export pyrophosphate (PPi) from cells. This did not explain, however, the presence of ANKH in tissues, such as brain, blood vessels and muscle. We now report that in cultured cells ANKH exports ATP, rather than PPi, and, unexpectedly, also citrat...
Alternative Titles
Full title
The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2434498931
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2434498931
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1008884
