Obeticholic acid reduces biliary and hepatic matrix metalloproteinases activity in rat hepatic ische...
Obeticholic acid reduces biliary and hepatic matrix metalloproteinases activity in rat hepatic ischemia/reperfusion injury
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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We have previously shown that obeticholic acid (OCA) upregulates the biliary excretion of asymmetric dimethylarginine (ADMA), an inhibitor of iNOS regulating the activity of matrix metalloproteinases (MMPs). Here, the effects of OCA on MMP-2 and MMP-9 activity in liver, bile and serum were evaluated after hepatic ischemia/reperfusion (I/R) injury....
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Obeticholic acid reduces biliary and hepatic matrix metalloproteinases activity in rat hepatic ischemia/reperfusion injury
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TN_cdi_plos_journals_2441546844
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2441546844
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0238543
