Footprint of the host restriction factors APOBEC3 on the genome of human viruses
Footprint of the host restriction factors APOBEC3 on the genome of human viruses
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
APOBEC3 enzymes are innate immune effectors that introduce mutations into viral genomes. These enzymes are cytidine deaminases which transform cytosine into uracil. They preferentially mutate cytidine preceded by thymidine making the 5'TC motif their favored target. Viruses have evolved different strategies to evade APOBEC3 restriction. Certain vir...
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Full title
Footprint of the host restriction factors APOBEC3 on the genome of human viruses
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TN_cdi_plos_journals_2443614857
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2443614857
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008718
