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Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamic...

Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2445951769

Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamics

About this item

Full title

Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamics

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-09, Vol.15 (9), p.e0239467-e0239467

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Dystrophin plays a vital role in maintaining muscle health, yet low mRNA expression, lengthy transcription time and the limitations of traditional in-situ hybridization (ISH) methodologies mean that the dynamics of dystrophin transcription remain poorly understood. RNAscope is highly sensitive ISH method that can be multiplexed, allowing detection...

Alternative Titles

Full title

Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2445951769

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2445951769

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0239467

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