Glutamate dehydrogenase as a biomarker for mitotoxicity; insights from furosemide hepatotoxicity in...
Glutamate dehydrogenase as a biomarker for mitotoxicity; insights from furosemide hepatotoxicity in the mouse
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Glutamate dehydrogenase (GLDH) is a liver-specific biomarker of hepatocellular damage currently undergoing qualification as a drug development tool. Since GLDH is located within the mitochondrial matrix, it has been hypothesized that it might also be useful in assessing mitotoxicity as an initiating event during drug-induced liver injury. According...
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Full title
Glutamate dehydrogenase as a biomarker for mitotoxicity; insights from furosemide hepatotoxicity in the mouse
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TN_cdi_plos_journals_2449653678
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2449653678
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0240562
