Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies
Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies
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Publisher
San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Scope and Contents
Contents
As a novel alternative to established surface display or combinatorial chemistry approaches for the discovery of therapeutic peptides, we present a method for the isolation of small, cysteine-rich domains from bovine antibody ultralong complementarity-determining regions (CDRs). We show for the first time that isolated bovine antibody knob domains...
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Full title
Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies
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TN_cdi_plos_journals_2451552205
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2451552205
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3000821
