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Humanization of yeast genes with multiple human orthologs reveals functional divergence between para...

Humanization of yeast genes with multiple human orthologs reveals functional divergence between para...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2460094537

Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs

About this item

Full title

Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2020-05, Vol.18 (5), p.e3000627-e3000627

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Despite over a billion years of evolutionary divergence, several thousand human genes possess clearly identifiable orthologs in yeast, and many have undergone lineage-specific duplications in one or both lineages. These duplicated genes may have been free to diverge in function since their expansion, and it is unclear how or at what rate ancestral...

Alternative Titles

Full title

Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2460094537

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2460094537

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3000627

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