Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
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Author / Creator
Robichon, Katharina , Maiwald, Tim , Schilling, Marcel , Schneider, Annette , Willemsen, Joschka , Salopiata, Florian , Teusel, Melissa , Kreutz, Clemens , Ehlting, Christian , Huang, Jun , Chakraborty, Sajib , Huang, Xiaoyun , Damm, Georg , Seehofer, Daniel , Lang, Philipp A. , Bode, Johannes G. , Binder, Marco , Bartenschlager, Ralf , Timmer, Jens and Klingmüller, Ursula
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The induction of an interferon-mediated response is the first line of defense against pathogens such as viruses. Yet, the dynamics and extent of interferon alpha (IFNα)-induced antiviral genes vary remarkably and comprise three expression clusters: early, intermediate and late. By mathematical modeling based on time-resolved quantitative data, we i...
Alternative Titles
Full title
Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
Authors, Artists and Contributors
Author / Creator
Maiwald, Tim
Schilling, Marcel
Schneider, Annette
Willemsen, Joschka
Salopiata, Florian
Teusel, Melissa
Kreutz, Clemens
Ehlting, Christian
Huang, Jun
Chakraborty, Sajib
Huang, Xiaoyun
Damm, Georg
Seehofer, Daniel
Lang, Philipp A.
Bode, Johannes G.
Binder, Marco
Bartenschlager, Ralf
Timmer, Jens
Klingmüller, Ursula
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2460983417
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2460983417
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008461