Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
About this item
Full title
Author / Creator
Robichon, Katharina , Maiwald, Tim , Schilling, Marcel , Schneider, Annette , Willemsen, Joschka , Salopiata, Florian , Teusel, Melissa , Kreutz, Clemens , Ehlting, Christian , Huang, Jun , Chakraborty, Sajib , Huang, Xiaoyun , Damm, Georg , Seehofer, Daniel , Lang, Philipp A , Bode, Johannes G , Binder, Marco , Bartenschlager, Ralf , Timmer, Jens and Klingmüller, Ursula
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The induction of an interferon-mediated response is the first line of defense against pathogens such as viruses. Yet, the dynamics and extent of interferon alpha (IFNα)-induced antiviral genes vary remarkably and comprise three expression clusters: early, intermediate and late. By mathematical modeling based on time-resolved quantitative data, we i...
Alternative Titles
Full title
Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
Authors, Artists and Contributors
Author / Creator
Maiwald, Tim
Schilling, Marcel
Schneider, Annette
Willemsen, Joschka
Salopiata, Florian
Teusel, Melissa
Kreutz, Clemens
Ehlting, Christian
Huang, Jun
Chakraborty, Sajib
Huang, Xiaoyun
Damm, Georg
Seehofer, Daniel
Lang, Philipp A
Bode, Johannes G
Binder, Marco
Bartenschlager, Ralf
Timmer, Jens
Klingmüller, Ursula
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2460983417
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2460983417
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008461
