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G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded...

G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2461501580

G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus

About this item

Full title

G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-11, Vol.15 (11), p.e0242380-e0242380

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Thyroid hormone (T3) inhibits thyrotropin-releasing hormone (TRH) synthesis in the hypothalamic paraventricular nucleus (PVN). Although the T3 receptor (TR) β2 is known to mediate the negative regulation of the prepro-TRH gene, its molecular mechanism remains unknown. Our previous studies on the T3-dependent negative regulation of the thyrotropin β...

Alternative Titles

Full title

G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2461501580

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2461501580

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0242380

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