Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation
Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Antigen cross presentation, whereby exogenous antigens are presented by MHC class I molecules to CD8+ T cells, is essential for generating adaptive immunity to pathogens and tumor cells. Following endocytosis, it is widely understood that protein antigens must be transferred from endosomes to the cytosol where they are subject to ubiquitination and...
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Full title
Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation
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TN_cdi_plos_journals_2464157136
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2464157136
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0238484
