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Missing value imputation in proximity extension assay-based targeted proteomics data

Missing value imputation in proximity extension assay-based targeted proteomics data

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2470011242

Missing value imputation in proximity extension assay-based targeted proteomics data

About this item

Full title

Missing value imputation in proximity extension assay-based targeted proteomics data

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-12, Vol.15 (12), p.e0243487-e0243487

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Targeted proteomics utilizing antibody-based proximity extension assays provides sensitive and highly specific quantifications of plasma protein levels. Multivariate analysis of this data is hampered by frequent missing values (random or left censored), calling for imputation approaches. While appropriate missing-value imputation methods exist, ben...

Alternative Titles

Full title

Missing value imputation in proximity extension assay-based targeted proteomics data

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2470011242

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2470011242

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0243487

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