The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in mu...
The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models
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Author / Creator
Katewa, Arna , Suto, Eric , Hui, Jessica , Heredia, Jose , Liang, Jie , Hackney, Jason , Anderson, Keith , Alcantar, Tuija M , Bacarro, Natasha , Dunlap, Debra , Eastham, Jeffrey , Paler-Martinez, Andres , Rairdan, Xin Y , Modrusan, Zora , Lee, Wyne P , Austin, Cary D , Lafkas, Daniel and Ghilardi, Nico
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease representing a serious unmet medical need. The disease is associated with the loss of self-tolerance and exaggerated B cell activation, resulting in autoantibody production and the formation of immune complexes that accumulate in the kidney, causing glomerulonephritis. TLR7, an impo...
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Full title
The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models
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TN_cdi_plos_journals_2478023407
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2478023407
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0244439
