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Membrane progesterone receptor induces meiosis in Xenopus oocytes through endocytosis into signaling...

Membrane progesterone receptor induces meiosis in Xenopus oocytes through endocytosis into signaling...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2479049941

Membrane progesterone receptor induces meiosis in Xenopus oocytes through endocytosis into signaling endosomes and interaction with APPL1 and Akt2

About this item

Full title

Membrane progesterone receptor induces meiosis in Xenopus oocytes through endocytosis into signaling endosomes and interaction with APPL1 and Akt2

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2020-11, Vol.18 (11), p.e3000901

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The steroid hormone progesterone (P4) mediates many physiological processes through either nuclear receptors that modulate gene expression or membrane P4 receptors (mPRs) that mediate nongenomic signaling. mPR signaling remains poorly understood. Here we show that the topology of mPRβ is similar to adiponectin receptors and opposite to that of G-pr...

Alternative Titles

Full title

Membrane progesterone receptor induces meiosis in Xenopus oocytes through endocytosis into signaling endosomes and interaction with APPL1 and Akt2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2479049941

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2479049941

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3000901

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