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Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrup...

Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrup...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2479450448

Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature

About this item

Full title

Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature

Publisher

United States: Public Library of Science

Journal title

PloS one, 2021-01, Vol.16 (1), p.e0245602-e0245602

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

With the advent of potent second-line anti-androgen therapy, we and others have observed an increased incidence of androgen receptor (AR)-null small cell or neuroendocrine prostate cancer (SCNPC) in metastatic castration-resistant prostate cancer (mCRPC). Our study was designed to determine the effect of cabozantinib, a multi-targeted tyrosine kina...

Alternative Titles

Full title

Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2479450448

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2479450448

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0245602

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