Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predi...
Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer
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Author / Creator
Dong, Zhexu , Dai, Lei , Zhang, Yong , Fang, Chao , Shi, Gang , Chen, Ye , Li, Junshu , Wang, Qin , Fu, Jiamei , Yu, Yan , Wang, Wenshuang , Cheng, Lin , Liu, Yi , Lin, Yi , Wang, Yuan , Wang, Qingnan , Wang, Huiling , Zhang, Hantao , Zhang, Yujing , Su, Xiaolan , Zhang, Shuang , Wang, Feng , Qiu, Meng , Zhou, Zongguang and Deng, Hongxin
Publisher
United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Tumor metastasis is the major cause of poor prognosis and mortality in colorectal cancer (CRC). However, early diagnosis of highly metastatic CRC is currently difficult. In the present study, we screened for a novel biomarker, GDNF family receptor alpha 1 (GFRA1) based on the expression and methylation data in CRC patients from The Cancer Genome Al...
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Full title
Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer
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TN_cdi_plos_journals_2479451660
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2479451660
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1009159
