Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nuclei
Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nuclei
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United States: Public Library of Science
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English
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United States: Public Library of Science
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FSHD is characterized by the misexpression of DUX4 in skeletal muscle. Although DUX4 upregulation is thought to be the pathogenic cause of FSHD, DUX4 is lowly expressed in patient samples, and analysis of the consequences of DUX4 expression has largely relied on artificial overexpression. To better understand the native expression profile of DUX4 a...
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Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nuclei
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TN_cdi_plos_journals_2479458717
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2479458717
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1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1008754
