Pharmacological upregulation of GLT-1 alleviates the cognitive impairments in the animal model of te...
Pharmacological upregulation of GLT-1 alleviates the cognitive impairments in the animal model of temporal lobe epilepsy
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United States: Public Library of Science
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English
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United States: Public Library of Science
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It is known that hippocampal epileptogenesis is accompanied by hyperexcitability, glutamate-related neuronal dysfunctions and consequently cognitive deficits. However, the neuroprotective role of astrocytic glutamate uptake through the Glutamate Transporter-1 (GLT-1) remains to be unknown in these processes. Therefore, to assess the effect of gluta...
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Pharmacological upregulation of GLT-1 alleviates the cognitive impairments in the animal model of temporal lobe epilepsy
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TN_cdi_plos_journals_2482650354
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2482650354
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0246068