Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development
Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development
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United States: Public Library of Science
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English
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United States: Public Library of Science
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SLFN11 has recently been reported to execute cancer cells harboring replicative stress induced by DNA damaging agents. However, the roles of SLFN11 under physiological conditions remain poorly understood. Germinal center B-cells (GCBs) undergo somatic hypermutations and class-switch recombination, which can cause physiological genotoxic stress. Hen...
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Full title
Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development
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TN_cdi_plos_journals_2483630117
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2483630117
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0237554
