Polygenic risk score validation using Korean genomes of 265 early-onset acute myocardial infarction...
Polygenic risk score validation using Korean genomes of 265 early-onset acute myocardial infarction patients and 636 healthy controls
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Author / Creator
Bhak, Youngjune , Jeon, Yeonsu , Jeon, Sungwon , Yoon, Changhan , Kim, Min , Blazyte, Asta , Kim, Yeonkyung , Kang, Younghui , Kim, Changjae , Lee, Sang Yeub , Bae, Jang-Whan , Kim, Weon , Kim, Yeo Jin , Shim, Jungae , Kim, Nayeong , Chun, Sung , Kim, Byoung-Chul , Kim, Byung Chul , Lee, Semin , Bhak, Jong and Shin, Eun-Seok
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The polygenic risk score (PRS) developed for coronary artery disease (CAD) is known to be effective for classifying patients with CAD and predicting subsequent events. However, the PRS was developed mainly based on the analysis of Caucasian genomes and has not been validated for East Asians. We aimed to evaluate the PRS in the genomes of Korean ear...
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Full title
Polygenic risk score validation using Korean genomes of 265 early-onset acute myocardial infarction patients and 636 healthy controls
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TN_cdi_plos_journals_2486455830
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2486455830
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0246538
