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Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingo...

Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2492268647

Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingonberry extract

About this item

Full title

Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingonberry extract

Publisher

United States: Public Library of Science

Journal title

PloS one, 2021-02, Vol.16 (2), p.e0247329-e0247329

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In this work, a new magnetic ligand fishing probe for discovery of DPP-IV inhibitory ligands was developed and it was tested as a proof of concept on the fruit extract of Vaccinium vitis-idaea (lingonberry). The ligands were shown to have appreciable dipeptidyl peptidase IV (DPP-IV) inhibitory activity (IC50: 31.8 μg mL-1).) Inhibition of DPP-IV is...

Alternative Titles

Full title

Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingonberry extract

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2492268647

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2492268647

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0247329

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