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Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein...

Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2493832104

Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein expression of Na+,K+-ATPase, FXYD1, and FXYD5 in cultured human skeletal muscle cells

About this item

Full title

Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein expression of Na+,K+-ATPase, FXYD1, and FXYD5 in cultured human skeletal muscle cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2021, Vol.16 (2), p.e0247377-e0247377

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Denervation reduces the abundance of Na+,K+-ATPase (NKA) in skeletal muscle, while reinnervation increases it. Primary human skeletal muscle cells, the most widely used model to study human skeletal muscle in vitro, are usually cultured as myoblasts or myotubes without neurons and typically do not contract spontaneously, which might affect their ab...

Alternative Titles

Full title

Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein expression of Na+,K+-ATPase, FXYD1, and FXYD5 in cultured human skeletal muscle cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2493832104

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2493832104

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0247377

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