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Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite...

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2499870177

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening

About this item

Full title

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening

Publisher

United States: Public Library of Science

Journal title

PloS one, 2021-03, Vol.16 (3), p.e0248139-e0248139

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

This work tries to help overcome the lack of relevant translational screening assays, as a limitation for the identification of novel analgesics for neuropathic pain. Hyperexcitability and neurite shortening are common adverse effects of antiviral and antitumor drugs, leading to neuropathic pain. Now, as seen in the drug screening that we developed...

Alternative Titles

Full title

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2499870177

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2499870177

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0248139

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