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Epigenomic characterization of latent HIV infection identifies latency regulating transcription fact...

Epigenomic characterization of latent HIV infection identifies latency regulating transcription fact...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2501884916

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

About this item

Full title

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2021-02, Vol.17 (2), p.e1009346-e1009346

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Transcriptional silencing of HIV in CD4 T cells generates a reservoir of latently infected cells that can reseed infection after interruption of therapy. As such, these cells represent the principal barrier to curing HIV infection, but little is known about their characteristics. To further our understanding of the molecular mechanisms of latency,...

Alternative Titles

Full title

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2501884916

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2501884916

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1009346

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