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L-phenylalanine attenuates high salt-induced hypertension in Dahl SS rats through activation of GCH1...

L-phenylalanine attenuates high salt-induced hypertension in Dahl SS rats through activation of GCH1...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2513232180

L-phenylalanine attenuates high salt-induced hypertension in Dahl SS rats through activation of GCH1-BH4

About this item

Full title

L-phenylalanine attenuates high salt-induced hypertension in Dahl SS rats through activation of GCH1-BH4

Publisher

United States: Public Library of Science

Journal title

PloS one, 2021-04, Vol.16 (4), p.e0250126-e0250126

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Amino acid metabolism plays an important role in controlling blood pressure by regulating the production of NO and ROS. The present study examined amino acid levels in the serum of Dahl SS rats and SS.13BN rats fed a low or high salt diet. We observed that 8 of 27 amino acids responded to a high salt diet in SS rats. Thus, we hypothesized that a de...

Alternative Titles

Full title

L-phenylalanine attenuates high salt-induced hypertension in Dahl SS rats through activation of GCH1-BH4

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2513232180

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2513232180

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0250126

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