Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient...
Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Inactivating mutations in either
TSC1
or
TSC2
cause Tuberous Sclerosis Complex, an autosomal dominant disorder, characterized by multi-system tumor and hamartoma development. Mutation and loss of function of
TSC1
and/or
TSC2
also occur in a variety of sporadic cancers, and rapamycin and related drugs show highly variable tre...
Alternative Titles
Full title
Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer
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Record Identifier
TN_cdi_plos_journals_2517338878
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2517338878
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0248380
