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Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory...

Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528216570

Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype

About this item

Full title

Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2021-04, Vol.17 (4), p.e1009430-e1009430

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In malaria-naïve children and adults,
Plasmodium falciparum
-infected red blood cells (
Pf
-iRBCs) trigger fever and other symptoms of systemic inflammation. However, in endemic areas where individuals experience repeated
Pf
infections over many years, the risk of
Pf
-iRBC-triggered inflammatory symptoms decreases with cumul...

Alternative Titles

Full title

Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2528216570

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528216570

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1009430

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