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Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic...

Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528218404

Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection

About this item

Full title

Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2021-04, Vol.17 (4), p.e1009117

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Gene editing is now routine in all prokaryotic and metazoan cells but has not received much attention in immune cells when the CRISPR-Cas9 technology was introduced in the field of mammalian cell biology less than ten years ago. This versatile technology has been successfully adapted for gene modifications in human myeloid cells and T cells, among...

Alternative Titles

Full title

Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2528218404

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528218404

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1009117

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