Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic...
Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Gene editing is now routine in all prokaryotic and metazoan cells but has not received much attention in immune cells when the CRISPR-Cas9 technology was introduced in the field of mammalian cell biology less than ten years ago. This versatile technology has been successfully adapted for gene modifications in human myeloid cells and T cells, among...
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Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection
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TN_cdi_plos_journals_2528218404
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528218404
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009117