The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and pro...
The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The high transmissibility of SARS-CoV-2 is related to abundant replication in the upper airways, which is not observed for the other highly pathogenic coronaviruses SARS-CoV and MERS-CoV. We here reveal features of the coronavirus spike (S) protein, which optimize the virus towards the human respiratory tract. First, the S proteins exhibit an intri...
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Full title
The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways
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TN_cdi_plos_journals_2528218475
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528218475
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009500
