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A human coronavirus evolves antigenically to escape antibody immunity

A human coronavirus evolves antigenically to escape antibody immunity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528219066

A human coronavirus evolves antigenically to escape antibody immunity

About this item

Full title

A human coronavirus evolves antigenically to escape antibody immunity

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2021-04, Vol.17 (4), p.e1009453-e1009453

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

There is intense interest in antibody immunity to coronaviruses. However, it is unknown if coronaviruses evolve to escape such immunity, and if so, how rapidly. Here we address this question by characterizing the historical evolution of human coronavirus 229E. We identify human sera from the 1980s and 1990s that have neutralizing titers against con...

Alternative Titles

Full title

A human coronavirus evolves antigenically to escape antibody immunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2528219066

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528219066

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1009453

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