A human coronavirus evolves antigenically to escape antibody immunity
A human coronavirus evolves antigenically to escape antibody immunity
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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There is intense interest in antibody immunity to coronaviruses. However, it is unknown if coronaviruses evolve to escape such immunity, and if so, how rapidly. Here we address this question by characterizing the historical evolution of human coronavirus 229E. We identify human sera from the 1980s and 1990s that have neutralizing titers against con...
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A human coronavirus evolves antigenically to escape antibody immunity
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TN_cdi_plos_journals_2528219066
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2528219066
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009453