Identification of novel and rare variants associated with handgrip strength using whole genome seque...
Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program
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Author / Creator
on behalf of the TOPMed Longevity and Healthy Aging Working Group , from the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium , TOPMed Longevity and Healthy Aging Working Group , Sarnowski, Chloé , Chen, Han , Biggs, Mary L. , Wassertheil-Smoller, Sylvia , Bressler, Jan , Irvin, Marguerite R. , Ryan, Kathleen A. , Karasik, David , Arnett, Donna K. , Cupples, L. Adrienne , Fardo, David W. , Gogarten, Stephanie M. , Heavner, Benjamin D. , Jain, Deepti , Kang, Hyun Min , Kooperberg, Charles , Mainous, Arch G. , Mitchell, Braxton D. , Morrison, Alanna C. , O’Connell, Jeffrey R. , Psaty, Bruce M. , Rice, Kenneth , Smith, Albert V. , Vasan, Ramachandran S. , Windham, B. Gwen , Kiel, Douglas P. , Murabito, Joanne M. and Lunetta, Kathryn L.
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Handgrip strength is a widely used measure of muscle strength and a predictor of a range of morbidities including cardiovascular diseases and all-cause mortality. Previous genome-wide association studies of handgrip strength have focused on common variants primarily in persons of European descent. We aimed to identify rare and ancestry-specific gen...
Alternative Titles
Full title
Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program
Authors, Artists and Contributors
Author / Creator
from the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
TOPMed Longevity and Healthy Aging Working Group
Sarnowski, Chloé
Chen, Han
Biggs, Mary L.
Wassertheil-Smoller, Sylvia
Bressler, Jan
Irvin, Marguerite R.
Ryan, Kathleen A.
Karasik, David
Arnett, Donna K.
Cupples, L. Adrienne
Fardo, David W.
Gogarten, Stephanie M.
Heavner, Benjamin D.
Jain, Deepti
Kang, Hyun Min
Kooperberg, Charles
Mainous, Arch G.
Mitchell, Braxton D.
Morrison, Alanna C.
O’Connell, Jeffrey R.
Psaty, Bruce M.
Rice, Kenneth
Smith, Albert V.
Vasan, Ramachandran S.
Windham, B. Gwen
Kiel, Douglas P.
Murabito, Joanne M.
Lunetta, Kathryn L.
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Record Identifier
TN_cdi_plos_journals_2547897962
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2547897962
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0253611
