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Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidatio...

Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidatio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2548981798

Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidation-reduction function as possible mechanism of altered sensitivity to ethanol sedation

About this item

Full title

Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidation-reduction function as possible mechanism of altered sensitivity to ethanol sedation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2021-07, Vol.16 (7), p.e0246224

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

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Scope and Contents

Contents

Chloride intracellular channels (CLICs) are a unique family of evolutionarily conserved metamorphic proteins, switching between stable conformations based on redox conditions. CLICs have been implicated in a wide variety biological processes including ion channel activity, apoptosis, membrane trafficking, and enzymatic oxidoreductase activity. Unde...

Alternative Titles

Full title

Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidation-reduction function as possible mechanism of altered sensitivity to ethanol sedation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2548981798

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2548981798

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0246224

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