In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose...
In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Loss of mitochondrial function contributes to fatigue, exercise intolerance and muscle weakness, and is a key factor in the disability that develops with age and a wide variety of chronic disorders. Here, we describe the impact of a first-in-class cardiolipin-binding compound that is targeted to mitochondria and improves oxidative phosphorylation c...
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Full title
In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial
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TN_cdi_plos_journals_2552047923
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2552047923
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0253849
