Novel EDGE encoding method enhances ability to identify genetic interactions
Novel EDGE encoding method enhances ability to identify genetic interactions
About this item
Full title
Author / Creator
Hall, Molly A. , Wallace, John , Lucas, Anastasia M. , Bradford, Yuki , Verma, Shefali S. , Müller-Myhsok, Bertram , Passero, Kristin , Zhou, Jiayan , McGuigan, John , Jiang, Beibei , Pendergrass, Sarah A. , Zhang, Yanfei , Peissig, Peggy , Brilliant, Murray , Sleiman, Patrick , Hakonarson, Hakon , Harley, John B. , Kiryluk, Krzysztof , Van Steen, Kristel , Moore, Jason H. and Ritchie, Marylyn D.
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Assumptions are made about the genetic model of single nucleotide polymorphisms (SNPs) when choosing a traditional genetic encoding: additive, dominant, and recessive. Furthermore, SNPs across the genome are unlikely to demonstrate identical genetic models. However, running SNP-SNP interaction analyses with every combination of encodings raises the...
Alternative Titles
Full title
Novel EDGE encoding method enhances ability to identify genetic interactions
Authors, Artists and Contributors
Author / Creator
Wallace, John
Lucas, Anastasia M.
Bradford, Yuki
Verma, Shefali S.
Müller-Myhsok, Bertram
Passero, Kristin
Zhou, Jiayan
McGuigan, John
Jiang, Beibei
Pendergrass, Sarah A.
Zhang, Yanfei
Peissig, Peggy
Brilliant, Murray
Sleiman, Patrick
Hakonarson, Hakon
Harley, John B.
Kiryluk, Krzysztof
Van Steen, Kristel
Moore, Jason H.
Ritchie, Marylyn D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2552289567
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2552289567
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1009534
