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Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei

Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2552289649

Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei

About this item

Full title

Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2021-06, Vol.17 (6), p.e1009696-e1009696

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Iron is an essential regulatory signal for virulence factors in many pathogens. Mammals and bloodstream form (BSF)
Trypanosoma brucei
obtain iron by receptor-mediated endocytosis of transferrin bound to receptors (TfR) but the mechanisms by which
T
.
brucei
subsequently handles iron remains enigmatic. Here, we analyse the transcri...

Alternative Titles

Full title

Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2552289649

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2552289649

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1009696

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