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Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Applicati...

Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Applicati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2561940204

Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Application to GSK Chagas Box

About this item

Full title

Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Application to GSK Chagas Box

Publisher

San Francisco: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2021-07, Vol.15 (7), p.e0009602-e0009602

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Chagas disease (CD) is a human disease caused by
Trypanosoma cruzi
. Whilst endemic in Latin America, the disease is spread around the world due to migration flows, being estimated that 8 million people are infected worldwide and over 10,000 people die yearly of complications linked to CD. Current chemotherapeutics is restricted to only two d...

Alternative Titles

Full title

Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Application to GSK Chagas Box

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2561940204

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2561940204

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0009602

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