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BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after per...

BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after per...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2561940430

BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after peripheral nerve injury

About this item

Full title

BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after peripheral nerve injury

Publisher

San Francisco: Public Library of Science

Journal title

PLoS biology, 2021-07, Vol.19 (7), p.e3001337

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Peripheral nerve injury–induced mechanical allodynia is often accompanied by abnormalities in the higher cortical regions, yet the mechanisms underlying such maladaptive cortical plasticity remain unclear. Here, we show that in male mice, structural and functional changes in the primary somatosensory cortex (S1) caused by peripheral nerve injury re...

Alternative Titles

Full title

BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after peripheral nerve injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2561940430

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2561940430

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3001337

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