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Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf...

Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2561940903

Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling

About this item

Full title

Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling

Publisher

San Francisco: Public Library of Science

Journal title

PLoS pathogens, 2021-07, Vol.17 (7), p.e1009732-e1009732

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

We have recently demonstrated that the function of T follicular helper (Tfh) cells from lymph nodes (LN) of HIV-infected individuals is impaired. We found that these cells were unable to provide proper help to germinal center (GC)-B cells, as observed by altered and inefficient anti-HIV antibody response and premature death of memory B cells. The u...

Alternative Titles

Full title

Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2561940903

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2561940903

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1009732

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