A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysre...
A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Type 1 diabetes (T1D) is an organ-specific autoimmune disease, whereby immune cell-mediated killing leads to loss of the insulin-producing β cells in the pancreas. Genome-wide association studies (GWAS) have identified over 200 genetic variants associated with risk for T1D. The majority of the GWAS risk variants reside in the non-coding regions of...
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Full title
A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation
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TN_cdi_plos_journals_2573409059
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2573409059
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0257265
