Deletion of the SELENOP gene leads to CNS atrophy with cerebellar ataxia in dogs
Deletion of the SELENOP gene leads to CNS atrophy with cerebellar ataxia in dogs
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
We investigated a hereditary cerebellar ataxia in Belgian Shepherd dogs. Affected dogs developed uncoordinated movements and intention tremor at two weeks of age. The severity of clinical signs was highly variable. Histopathology demonstrated atrophy of the CNS, particularly in the cerebellum. Combined linkage and homozygosity mapping in a family w...
Alternative Titles
Full title
Deletion of the SELENOP gene leads to CNS atrophy with cerebellar ataxia in dogs
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2573455539
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2573455539
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1009716
