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The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient...

The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2582586650

The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal

About this item

Full title

The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2021-09, Vol.17 (9), p.e1009364-e1009364

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In behavioral learning, reward-related events are encoded into phasic dopamine (DA) signals in the brain. In particular, unexpected reward omission leads to a phasic decrease in DA (DA dip) in the striatum, which triggers long-term potentiation (LTP) in DA D2 receptor (D2R)-expressing spiny-projection neurons (D2 SPNs). While this LTP is required f...

Alternative Titles

Full title

The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2582586650

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2582586650

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1009364

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