Low-dose IL-2 therapy invigorates CD8+ T cells for viral control in systemic lupus erythematosus
Low-dose IL-2 therapy invigorates CD8+ T cells for viral control in systemic lupus erythematosus
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Author / Creator
Zhou, Pengcheng , Chen, Jiali , He, Jing , Zheng, Ting , Yunis, Joseph , Makota, Victor , Alexandre, Yannick O. , Gong, Fang , Zhang, Xia , Xie, Wuxiang , Li, Yuhui , Shao, Miao , Zhu, Yanshan , Sinclair, Jane E. , Miao, Miao , Chen, Yaping , Short, Kirsty R. , Mueller, Scott N. , Sun, Xiaolin , Yu, Di and Li, Zhanguo
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Autoimmune diseases are often treated by glucocorticoids and immunosuppressive drugs that could increase the risk for infection, which in turn deteriorate disease and cause mortality. Low-dose IL-2 (Ld-IL2) therapy emerges as a new treatment for a wide range of autoimmune diseases. To examine its influence on infection, we retrospectively studied 6...
Alternative Titles
Full title
Low-dose IL-2 therapy invigorates CD8+ T cells for viral control in systemic lupus erythematosus
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Record Identifier
TN_cdi_plos_journals_2598100917
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2598100917
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009858
