Tenofovir disoproxil fumarate directly ameliorates liver fibrosis by inducing hepatic stellate cell...
Tenofovir disoproxil fumarate directly ameliorates liver fibrosis by inducing hepatic stellate cell apoptosis via downregulation of PI3K/Akt/mTOR signaling pathway
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Antifibrotic agent for the treatment of liver fibrosis has not been developed so far. Long term treatment of chronic hepatitis B patients with antiviral drugs tenofovir disoproxil fumarate (TDF) and entecavir (ETV) results in the regression of liver fibrosis, but the underlying mechanism has not been clarified. Therefore, we aimed to investigate th...
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Tenofovir disoproxil fumarate directly ameliorates liver fibrosis by inducing hepatic stellate cell apoptosis via downregulation of PI3K/Akt/mTOR signaling pathway
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TN_cdi_plos_journals_2608081706
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2608081706
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0261067
