TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction
TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Interferons play a critical role in regulating host immune responses to SARS-CoV-2, but the interferon (IFN)-stimulated gene (ISG) effectors that inhibit SARS-CoV-2 are not well characterized. The IFN-inducible short isoform of human nuclear receptor coactivator 7 (NCOA7) inhibits endocytic virus entry, interacts with the vacuolar ATPase, and promo...
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Full title
TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction
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TN_cdi_plos_journals_2610939324
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2610939324
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009820
