Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials
Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials
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Author / Creator
Fischinger, Stephanie , Cizmeci, Deniz , Deng, Davy , Grant, Shannon P , Frahm, Nicole , McElrath, Julie , Fuchs, Jonathan , Bart, Pierre-Alexandre , Pantaleo, Giuseppe , Keefer, Michael , O Hahn, William , Rouphael, Nadine , Churchyard, Gavin , Moodie, Zoe , Donastorg, Yeycy , Streeck, Hendrik and Alter, Galit
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Despite the advent of long-acting anti-retroviral therapy able to control and prevent infection, a preventative vaccine remains a global priority for the elimination of HIV. The moderately protective RV144 vaccine trial suggested functional IgG1 and IgG3 antibodies were a potential correlate of protection, but the RV144-inspired HVTN702 validation...
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Full title
Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials
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TN_cdi_plos_journals_2610939555
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2610939555
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1010016